CD8

Clone: 144B

Catalog # 10173

Colon, CD8 (144B)

Host: Mouse

Application: IHC-P

Species reactivity: Human. Others not tested.

Description: CD8 is a cell surface receptor, it binds to MHC class 1 and plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen

Impresszum

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