Catalog # 10118
Species reactivity: Human. Others not tested.
Description: DOG-1 is expressed ubiquitously in gastrointestinal stromal tumors (GIST) irrespective of kit or PDGFR alpha mutation status. This antibody to DOG-1 may aid in the diagnosis of GISTs, including PDGFRA mutants that fail to express KIT antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the KIT tyrosine kinase.