MART-1 (Melan-A)

Clone: A103

Catalog # 10133

MART-1 (Melan-A)

Melanoma, MART-1, Melan-A (A103)

Host: Mouse

Application: IHC-P

Species reactivity: Human. Others not tested.

Description: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells - 1) or Melan-A. MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. MART-1 is present in melanosomes and endoplasmic reticulum. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. This antibody is a useful marker for identification of metastatic melanomas.